sugar, free radicals and your health

There's a story on Reuters Newswire that really impacts me. As anyone who knows me realizes, I live for sugar. Soda, candy, cookies, kid's cereal---any source will do.

Well, according to the story, taking vitamins and eating foods rich in antioxidants is BAD for you. Go figure. There is a justification for this unexpected finding. Here's the story from Reuters:

Life can be sweeter if you cut out the sugar
Tue Oct 2, 2007 12:53pm EDT
By Michael Kahn

LONDON (Reuters) - Giving up sweets and avoiding vitamins could help you live longer, German researchers said on Tuesday.

They found that restricting glucose -- a simple sugar found in foods such as sweets that is a primary source of energy for the body -- set off a process that extended the life span of some worms by up to 25 percent.

The key was boosting the level of "free radicals" -- unstable molecules that can damage the body and which people often try to get rid of by consuming food or drinks rich in anti-oxidants such as vitamin E, they said in a study published in the journal Cell Metabolism.

Restricting glucose first spurred the worms to generate more free radicals, but then they quickly built up long-lasting defenses against them, said Michael Ristow, an endocrinologist at the University of Jena and the German Institute of Human Nutrition, who led the study.

"During the process, the worm generates more free radicals, which activates defenses against free radicals within the worm," he said in a telephone interview. "The bad thing in the end promotes something good."

The body needs glucose, but taking in too much was unhealthy, Ristow said.

Scientists have long known that restricting calorie intake in worms and monkeys increases longevity, and the study narrowed that idea further, to glucose.

The study also for the first time points to a possible reason why antioxidants -- long thought to promote health -- might do more harm than good, Ristow said.

The German team used a chemical that blocked the worms' ability to process glucose in a treatment that extended their life span by up to 25 percent, the equivalent of 15 years in humans.

The worms unable to depend on glucose increased energy power sources in certain cells for fuel. That activity produced more free radicals, which in turn generated enzymes that strengthened long-time protection against the harmful molecules, Ristow said.

However, antioxidants and vitamins given to some worms erased these benefits by neutralizing free radicals and preventing the body from generating the defenses, Ristow said.

"These latter findings tentatively suggest that the widespread use of antioxidants as human food supplements may exert undesirable effects," the researchers wrote.

© Reuters 2006. All rights reserved.

Personally I find the guideline of not eating antioxidant rich food quite easy to follow. No vitamin supplements? Also easy. But no glucose? That's like a wooden stake in a vampire's heart. Life would no longer be worth living.

I'll take 15 years less of a life filled with wonderful tasty sugar over no sugar at all. Damn researchers don't know when to mind their own business!


Paros Shepherd said…
I would like to see a deeper article on this research. The Reuters report mixes two opposing phenomena: the homeopathic effect of introducing a minute poison to stimulate defense versus long term positive nutrition.
I am guessing like most other things moderation is the key.
GA Girl said…
Worms don't know anything! Let's hope this is one of those findings that can't be replicated in humans. I like my antioxidants.
Shephard said…
Not being a scientist, I was already set to advocate moderation too. I have to admit... the continual contradiction chain that is science can be infuriating. I think most reports make huge leaps in interpretation. But admittedly, I'm not going to do the research either. So I'm stuck with siding with moderation in the face of so much rat-and-worm-based contradiction. Still, as presented, it's actually very interesting and thought-provoking.

kenju said…
Shephard said it well for me, Dave. And you, of all people, should know that in a short time, there will be a study to contradict this one. There almost always is.
SassyAssy said…
Maybe you should research the benefits of eating tons of sugar.
Michael Manning said…
Ah, good post! THis reminds me of various debates about coffee--which I refuse to cease in the mornings!

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